Vortrag

Name:	Dr. Niamh Connolly
	Physiology & Medical Physics Department Royal College of Surgeons in Ireland
	Homepage (externer Link)
Termin/Ort:	Donnerstag, 09.11.2017 17:00 Uhr im Gebäude 28 / Raum 27
Thema:	Using systems modelling to investigate bioenergetic dysfunction in Alzheimer’s disease

Abstract:

Mitochondrial bioenergetic dysfunction is implicated in neurodegenerative diseases such as Parkinson’s, Alzheimer’s and Huntington’s Diseases. It is unknown, however, whether mitochondrial dysfunction is sufficient to trigger neurodegeneration, or whether it constitutes an additional risk factor. As part of the interdisciplinary, multi-lab consortium, ‘Cellular Bioenergetics in Neurodegenerative Diseases’ (CeBioND; cebiond.org), we are combining systems modelling with in vitro experiments in a cellular model of Alzheimer’s Disease, to holistically investigate the impact of neurodegenerative defects on mitochondrial bioenergetic output.

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