Talk
| Name: | Dr. Niamh Connolly |
| Physiology & Medical Physics Department, Royal College of Surgeons in Ireland | |
| Homepage (external Link) | |
| Date/Location: | Thursday, November 09th 2017, 5 pm, Building 28 / Room 27 |
| Title: | Using systems modelling to investigate bioenergetic dysfunction in Alzheimer’s disease |
Abstract:
Mitochondrial bioenergetic dysfunction is implicated in neurodegenerative diseases such as Parkinson’s, Alzheimer’s and Huntington’s Diseases. It is unknown, however, whether mitochondrial dysfunction is sufficient to trigger neurodegeneration, or whether it constitutes an additional risk factor. As part of the interdisciplinary, multi-lab consortium, ‘Cellular Bioenergetics in Neurodegenerative Diseases’ (CeBioND; cebiond.org), we are combining systems modelling with in vitro experiments in a cellular model of Alzheimer’s Disease, to holistically investigate the impact of neurodegenerative defects on mitochondrial bioenergetic output.
Interested guests are welcome!