Dr. Anna Dittrich
2024
Essay
Detection, isolation and characterization of phage-host complexes using BONCAT and click chemistry
Hellwig, Patrick; Dittrich, Anna; Heyer, Robert; Reichl, Udo; Benndorf, Dirk
In: Frontiers in microbiology - Lausanne : Frontiers Media, Bd. 15 (2024), Artikel 1434301, insges. 12 S., 1 Online-Ressource (12 Seiten)
Peer-reviewed journal article
Dysregulated Gab1 signalling in triple negative breast cancer
Bongartz, Hannes; Mehlwald, Nora; Seiß, Elena A.; Schumertl, Tim; Naß, Norbert; Dittrich, Anna
In: Cell communication and signaling - London : Biomed Central, Bd. 22 (2024), Artikel 161, insges. 19 S.
2023
Peer-reviewed journal article
Non-canonical STAT3 function reduces REDD1 transcription
Köhler, Nadine; Wundrack, Nicole; Schulz, Svenja; Bartonitz, Florian; Schaper, Fred; Dittrich, Anna
In: The FEBS journal / Vereinigung der Europäischen Biochemischen Gesellschaften - Oxford [u.a.] : Wiley-Blackwell, Bd. 290 (2023), Heft 7, S. 1765-1781
Quantification of total and phosphorylated STAT3 by calibrated western blotting
Köhler, Nadine; Miri, Niloufarsadat; Dittrich, Anna
In: STAR Protocols - Cambridge, MA : Cell Press, Bd. 4 (2023), Heft 3, Artikel 102508, insges. 19 S.
Quantification of membrane-bound cytokine receptors by calibrated flow cytometry
Miri, Niloufarsadat; Köhler, Nadine; Dittrich, Anna
In: STAR Protocols - Cambridge, MA : Cell Press, Bd. 4 (2023), Heft 3, Artikel 102511, insges. 14 S.
2022
Peer-reviewed journal article
Decoding cellular communication - an information theoretic perspective on cytokine and endocrine signaling
Schaper, Fred; Jetka, Tomasz; Dittrich, Anna
In: Current opinion in endocrine and metabolic research - Amsterdam : Elsevier . - 2022
2021
Peer-reviewed journal article
The tyrosine phosphatase SHP2 increases robustness and information transfer within IL-6-induced JAK/STAT signalling
Fiebelkow, Jessica; Guendel, André; Guendel, Beate; Mehwald, Nora; Jetka, Tomasz; Komorowski, Michal; Waldherr, Steffen; Schaper, Fred; Dittrich, Anna
In: Cell communication and signaling - London: Biomed Central, Bd. 19 (2021), 1, insges. 19 S.
2020
Peer-reviewed journal article
Hepatocyte KLF6 expression affects FXR signalling and the clinical course of primary sclerosing cholangitis
Sydor, Svenja; Manka, Paul Peter; Buren, Lea; Theurer, Sarah; Schwertheim, Suzan; Best, Jan; Heegsma, Janette; Saeed, Ali; Vetter, Diana; Schlattjan, Martin; Dittrich, Anna; Fiel, Maria Isabel; Baba, Hideo Andreas; Dechêne, Alexander; Cubero, Francisco Javier; Gerken, Guido; Canbay, Ali E.; Moshage, Han; Friedman, Scott L.; Faber, Klaas Nico; Bechmann, Lars Peter
In: Liver international - Oxford : Wiley-Blackwell, Bd. 40 (2020), Heft 9, S. 2172-2181
2019
Peer-reviewed journal article
Intragenic regulation of SOCS3 isoforms
Klepsch, Oliver; Namer, Lise Sarah; Köhler, Nadine; Kaempfer, Raymond; Dittrich, Anna; Schaper, Fred
In: Cell communication and signaling - London: Biomed Central, Volume 17 (2019), 1, Artikel 70, insgesamt 15 Seiten
Response to IL-6 trans- and IL-6 classic signalling is determined by the ratio of the IL-6 receptor α to gp130 expression - fusing experimental insights and dynamic modelling
Reeh, Heike; Rudolph, Nadine; Billing, Ulrike; Christen, Henrike; Streif, Stefan; Bullinger, Eric; Schliemann-Bullinger, Monica; Findeisen, Rolf; Schaper, Fred; Huber, Heinrich; Dittrich, Anna
In: Cell communication and signaling - London: Biomed Central, Vol. 17.2019, 1, Art. 17:46, insgesamt 21 Seiten
Robustness and information transfer within IL-6-induced JAK/STAT signalling
Billing, Ulrike; Jetka, Tomasz; Nortmann, Lukas; Wundrack, Nicole; Komorowski, Michal; Waldherr, Steffen; Schaper, Fred; Dittrich, Anna
In: Communications biology - London: Springer Nature, Vol. 2.2019, Art. 27, insgesamt 14 S.
2018
Peer-reviewed journal article
Quantitative proteomics and systems analysis of cultured H9C2 cardiomyoblasts during differentiation over time supports a function follows form model of differentiation
Kankeu, Cynthia; Clarke, Kylie; Van Haver, Delphi; Gevaert, Kris; Impens, Francis; Dittrich, Anna; Roderick, H. Llewelyn; Passante, Egle; Huber, Heinrich
In: Molecular omics: research in proteomics, transcriptomics, metabolomics and other omics sciences - Cambridge: Royal Society of Chemistry, 2018[Online first]
2016
Peer-reviewed journal article
Interleukin-6 influences stress-signalling by reducing the expression of the mTOR-Inhibitor REDD1 in a STAT3-dependent manner
Pinno, Jessica; Bongartz, Hannes; Klepsch, Oliver; Wundrack, Nicole; Poli, Valeria; Schaper, Fred; Dittrich, Anna
In: Cellular signalling - Amsterdam [u.a.]: Elsevier Science, 1989, Bd. 28.2016, 8, S. 907-916
2015
Peer-reviewed journal article
A two-level approach for fusing early signaling events and long term cellular responses
Rudolph, Nadine; Meyer, Tina; Franzen, Kristina; Garbers, Christoph; Schaper, Fred; Streif, Stefan; Dittrich, Anna; Findeisen, Rolf
In: IFAC-PapersOnLine/ Internationale Förderung für Automatische Lenkung - Frankfurt: Elsevier, 2015, Bd. 48.2015, 8, S. 1228-1233[Kongress: 9th IFAC Symposium on Advanced Control of Chemical Processes ADCHEM 2015, Whistler, Canada, 7-10 June, 2015]
Systems biology of IL-6, IL-12 family cytokines
Dittrich, Anna; Hessenkemper, Wiebke; Schaper, Fred
In: Cytokine & growth factor reviews - Amsterdam [u.a.]: Elsevier Science, Bd. 26.2015, 5, S. 595-602
2013
Book chapter
Determination of protein turnover rates in the JAK/STAT pathway using a radioactive pulse-chase approach
Dittrich, Anna; Siewert, Elmar; Schaper, Fred
In: JAK-STAT signalling: methods and protocols / ed. by Sandra E. Nicholson and Nicos A. Nicola: methods and protocols - New York [u.a.]: Humana Pr., 2013 . - 2013, S. 69-80 - (Methods in molecular biology; 967)
Peer-reviewed journal article
JAK/STAT signalling - an executable model assembled from molecule-centred modules demonstrating a module-oriented database concept for systems and synthetic biology
Blätke, Mary Ann; Dittrich, Anna; Rohr, Christian; Heiner, Monika; Schaper, Fred; Marwan, Wolfgang
In: Molecular BioSystems - Cambridge: Royal Society of Chemistry, 2005, Bd. 9.2013, S. 1290-1307
2012
Book chapter
JAK-STAT signalling as example for a database-supported modular modelling concept
Blätke, Mary Ann; Dittrich, Anna; Heiner, Monika; Schaper, Fred; Marwan, Wolfgang
In: Computational Methods in Systems Biology / Gilbert , David - Berlin, Heidelberg : Springer ; Gilbert, David . - 2012, S. 362-365 - (Lecture Notes in Bioinformatics; 7605) Kongress: CMSB 2012 10 London, UK 2012.10.03-05
Original article in peer-reviewed international journal
Glucocorticoids increase interleukin-6 dependent gene induction by interfering with the expression of the SOCS 3 feedback inhibitor
Dittrich, Anna; Khouri, Christina; Sackett, Sara Dutton; Ehlting, Christian; Böhmer, Oliver; Albrecht, Ute; Bode, Johannes G.; Trautwein, Christian; Schaper, Fred
In: Hepatology. - Hoboken, NJ : Wiley Interscience, Bd. 55.2012, 1, S. 256-266
Model-driven experimental analysis of the function of SHP-2 in IL-6-induced Jak/STAT signaling
Dittrich, Anna; Quaiser, Tom; Khouri, Christina; Görtz, Dieter; Mönnigmann, Martin; Schaper, Fred
In: Molecular BioSystems. - Cambridge : Royal Society of Chemistry, 8, S. 2119-2134, 2012
Interleukin-6 signalling - more than Jaks and STATs
Eulenfeld, René; Dittrich, Anna; Khouri, Christina; Müller, Pia J.; Mütze, Barbara; Wolf, Alexandra; Schaper, Fred
In: European journal of cell biology. - Amsterdam : Elsevier, Bd. 91.2012, 6/7, S. 486-495
2011
Original article in peer-reviewed international journal
Glucagon counteracts interleukin-6-dependent gene expression by redundant action of EPAC and PKA
Khouri, Christina; Dittrich, Anna; Sackett, Sara Dutton; Denecke, Bernd; Trautwein, Christian; Schaper, Fred
In: Biological chemistry - Berlin [u.a.]: de Gruyter, Bd. 392.2011, S. 1123-1134
A simple work flow for biologically inspired model reduction - application to early JAK-STAT signaling
Quaiser, Tom; Dittrich, Anna; Schaper, Fred; Mönnigmann, Martin
In: BMC systems biology - London: BioMed Central, Bd. 5.2011, 30, insges. 30 S.