Anna Dittrich

Wiss. Mitarbeiterin

Dr. rer. nat. Anna Dittrich

Institut für Biologie (IBIO)
Systembiologie
Universitätsplatz 2, 39106, Magdeburg, G28-209
Publikationen

2020

Begutachteter Zeitschriftenartikel

Sydor, Svenja;  Manka, Paul;  Buren, Lea;  Theurer, Sarah;  Schwertheim, Suzan;  Best, Jan;  Heegsma, Janette;  Saeed, Ali;  Vetter, Diana;  Schlattjan, Martin;  Dittrich, Anna;  Fiel, Maria Isabel;  Baba, Hideo A.;  Dechêne, Alexander;  Cubero, Francisco Javier;  Gerken, Guido;  Canbay, Ali;  Moshage, Han;  Friedman, Scott L.;  Faber, Klaas Nico;  Bechmann, Lars 

Hepatocyte KLF6 expression affects FXR signalling and the clinical course of primary sclerosing cholangitis
In: Liver international: official journal of the International Association for the Study of the Liver - Oxford: Wiley-Blackwell, 2003 . - 2020

2019

Begutachteter Zeitschriftenartikel

Klepsch, Oliver;  Namer, Lise Sarah;  Köhler, Nadine;  Kaempfer, Raymond;  Dittrich, Anna;  Schaper, Fred 

Intragenic regulation of SOCS3 isoforms
In: Cell communication and signaling - London: Biomed Central, Volume 17 (2019), 1, Artikel 70, insgesamt 15 Seiten

Reeh, Heike;  Rudolph, Nadine;  Billing, Ulrike;  Christen, Henrike;  Streif, Stefan;  Bullinger, Eric;  Schliemann-Bullinger, Monica;  Findeisen, Rolf;  Schaper, Fred;  Huber, Heinrich;  Dittrich, Anna 

Response to IL-6 trans- and IL-6 classic signalling is determined by the ratio of the IL-6 receptor α to gp130 expression - fusing experimental insights and dynamic modelling
In: Cell communication and signaling - London: Biomed Central, 2003, Vol. 17.2019, 1, Art. 17:46, insgesamt 21 Seiten

Billing, Ulrike;  Jetka, Tomasz;  Nortmann, Lukas;  Wundrack, Nicole;  Komorowski, Michal;  Waldherr, Steffen;  Schaper, Fred;  Dittrich, Anna 

Robustness and information transfer within IL-6-induced JAK/STAT signalling
In: Communications biology - London: Springer Nature, Vol. 2.2019, Art. 27, insgesamt 14 S.

2018

Begutachteter Zeitschriftenartikel

Kankeu, Cynthia;  Clarke, Kylie;  Van Haver, Delphi;  Gevaert, Kris;  Impens, Francis;  Dittrich, Anna;  Roderick, H. Llewelyn;  Passante, Egle;  Huber, Heinrich 

Quantitative proteomics and systems analysis of cultured H9C2 cardiomyoblasts during differentiation over time supports a function follows form model of differentiation
In: Molecular omics: research in proteomics, transcriptomics, metabolomics and other omics sciences - Cambridge: Royal Society of Chemistry, 2018

2016

Begutachteter Zeitschriftenartikel

Pinno, Jessica;  Bongartz, Hannes;  Klepsch, Oliver;  Wundrack, Nicole;  Poli, Valeria;  Schaper, Fred;  Dittrich, Anna 

Interleukin-6 influences stress-signalling by reducing the expression of the mTOR-Inhibitor REDD1 in a STAT3-dependent manner
In: Cellular signalling - Amsterdam [u.a.]: Elsevier Science, Bd. 28.2016, 8, S. 907-916

2015

Begutachteter Zeitschriftenartikel

Rudolph, Nadine;  Meyer, Tina;  Franzen, Kristina;  Garbers, Christoph;  Schaper, Fred;  Streif, Stefan;  Dittrich, Anna;  Findeisen, Rolf 

A two-level approach for fusing early signaling events and long term cellular responses
In: IFAC-PapersOnLine/ Internationale Förderung für Automatische Lenkung - Frankfurt: Elsevier, 2015, Bd. 48.2015, 8, S. 1228-1233

Dittrich, Anna;  Hessenkemper, Wiebke;  Schaper, Fred 

Systems biology of IL-6, IL-12 family cytokines
In: Cytokine & growth factor reviews - Amsterdam [u.a.]: Elsevier Science, Bd. 26.2015, 5, S. 595-602

2013

Begutachteter Zeitschriftenartikel

Blätke, Mary Ann;  Dittrich, Anna;  Rohr, Christian;  Heiner, Monika;  Schaper, Fred;  Marwan, Wolfgang 

JAK/STAT signalling - an executable model assembled from molecule-centred modules demonstrating a module-oriented database concept for systems and synthetic biology
In: Molecular BioSystems - Cambridge: Royal Society of Chemistry, 2005, Bd. 9.2013, S. 1290-1307

Buchbeitrag

Dittrich, Anna;  Siewert, Elmar;  Schaper, Fred 

Determination of protein turnover rates in the JAK/STAT pathway using a radioactive pulse-chase approach
In: JAK-STAT signalling: methods and protocols / ed. by Sandra E. Nicholson and Nicos A. Nicola: methods and protocols - New York [u.a.]: Humana Pr., 2013 . - 2013, S. 69-80 - (Methods in molecular biology; 967)

2012

Buchbeitrag

Blätke, Mary Ann;  Dittrich, Anna;  Heiner, Monika;  Schaper, Fred;  Marwan, Wolfgang 

JAK-STAT signalling as example for a database-supported modular modelling concept
In: Gilbert, David: : Computational Methods in Systems Biology. - Berlin : Springer, S. 362-365, 2012 - (Lecture Notes in Bioinformatics; 7605)

Originalartikel in begutachteter internationaler Zeitschrift

Dittrich, Anna;  Khouri, Christina;  Sackett, Sara Dutton;  Ehlting, Christian;  Böhmer, Oliver;  Albrecht, Ute;  Bode, Johannes G.;  Trautwein, Christian;  Schaper, Fred 

Glucocorticoids increase interleukin-6 dependent gene induction by interfering with the expression of the SOCS 3 feedback inhibitor
In: Hepatology. - Hoboken, NJ : Wiley Interscience, Bd. 55.2012, 1, S. 256-266

Eulenfeld, René;  Dittrich, Anna;  Khouri, Christina;  Müller, Pia J.;  Mütze, Barbara;  Wolf, Alexandra;  Schaper, Fred 

Interleukin-6 signalling - more than Jaks and STATs
In: European journal of cell biology. - Amsterdam : Elsevier, Bd. 91.2012, 6/7, S. 486-495

Dittrich, Anna;  Quaiser, Tom;  Khouri, Christina;  Görtz, Dieter;  Mönnigmann, Martin;  Schaper, Fred 

Model-driven experimental analysis of the function of SHP-2 in IL-6-induced Jak/STAT signaling
In: Molecular BioSystems. - Cambridge : Royal Society of Chemistry, 8, S. 2119-2134, 2012

2011

Originalartikel in begutachteter internationaler Zeitschrift

Quaiser, Tom;  Dittrich, Anna;  Schaper, Fred;  Mönnigmann, Martin 

A simple work flow for biologically inspired model reduction - application to early JAK-STAT signaling
In: BMC systems biology - London: BioMed Central, Bd. 5.2011, 30, insges. 30 S.

Khouri, Christina;  Dittrich, Anna;  Sackett, Sara Dutton;  Denecke, Bernd;  Trautwein, Christian;  Schaper, Fred 

Glucagon counteracts interleukin-6-dependent gene expression by redundant action of EPAC and PKA
In: Biological chemistry - Berlin [u.a.]: de Gruyter, Bd. 392.2011, S. 1123-1134

Vita
09/2004Vordiplom in Biologie Heinrich-Heine Universität Düsseldorf
09/2007Diplom in Biologie RWTH Aachen
10/2007-09/2009Zusatzstudium Wirtschaftswissenschaften RWTH Aachen
10/2007-05/2010Institut für Biochemie & Molekularbiologie
RWTH Aachen
seit 06/2010Institut für Biologie, Lehrstuhl für Systembiologie
OvGU Magdeburg
03/2012Dissertation an der OvGU Magdeburg
01/2014-04/2014Gastwissenschaftlerin, Keio University Tokyo
Kooperationen
  • Prof. Dr. Stefan Rose-John, Christian-Albrechts-Universität Kie
  • Prof. Dr. Jürgen Scheller, Heinrich-Heine-Universität Düsseldorf
  • Prof. Dr. Rolf Findeisen, Otto-von-Guericke Universität Magdeburg
  • Prof. Akihiko Yoshimura, Keio University School of Medicine
  • Conaris Research Institute AG, Kiel
  • Prof. Dr. Raymond Kaempfer, Hebrew University, Jerusalem, Israel
Profil
Signaltransduktion
Interleukin-6
JAK/STAT
SHP2
SOCS3
Systembiologie
Service
Signaltransduktionsanalyse
Intrazelluläre FACS Analysen
Projekte
Lehrveranstaltungen

Letzte Änderung: 14.12.2018 - Ansprechpartner: Prof. Dr. Fred Schaper